Stat3 y750
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Stat3 y750
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WebReceive email alerts when new plasmids with this gene become available. Log in to subscribe to Addgene Alerts. Description signal transducer and activator of transcription 3. Also known as ADMIO, ADMIO1, APRF, HIES. Species Homo sapiens. Entrez ID 6774. MGC ID BC000627, BC014482. National Center for Biotechnology Information
WebMar 14, 2024 · Our findings identified an anti-tumor activity of Stattic by suppressing STAT3 Y705 phosphorylation, indicating its potential of Stattic as an intervention for PC. Results … WebAug 20, 2014 · 目前，多项研究证 stat3信号通路的干预是多种人类肿瘤治疗有效 目前，多项研究证实 ，stat3 胃癌细胞的多种生物学行为包括侵袭、迁移 附、增殖、凋亡等关 2．1stat3 胃癌细胞中异常表达 人们在对 多数恶性肿瘤(肝癌 、胃癌 stat3呈现高表达，且 stat3 与恶性 …
WebSep 1, 2024 · STAT3 hyper–immunoglobulin E syndrome (STAT3-HIES) is a rare primary immunodeficiency syndrome characterized by elevated serum immunoglobulin E levels, eczema, recurrent skin and respiratory tract infections, and several gastrointestinal (GI) problems. GI manifestations, such as gastroesophageal reflux disease, dysphagia, … WebSTAT3 GOF disease) is a rare genetic disorder of the immune system. STAT3 GOF disease is named after the gene that causes it, STAT3 (s. ignal . transducer and activator of transcription 3), and the effect caused by mutations in STAT3 —gain-of-function, meaning that the gene’s protein becomes overactive. STAT3
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WebFlow cytometric analysis of Stat3 (pY705). Human whole blood was collected in the presence of heparin. Whole blood was either left unstimulated (unshaded) or stimulated (shaded) with recombinant human IL-6 (Cat. No. 550071) at 100 ng/mL for 15 min at 37 °C. Cells were lysed and fixed in a single step using BD Phosflow™ Lyse/Fix buffer (Cat. easy-wire stationWebSep 24, 2024 · As a point of convergence for numerous oncogenic signaling pathways, signal transducer and activator of transcription 3 (STAT3) is central in regulating the anti-tumor immune response. STAT3 is broadly hyperactivated both in cancer and non-cancerous cells within the tumor ecosystem and plays important roles in inhibiting the … easy wire wrapped pendantWebApplications. 1/500. 1/2000 - 1/20000. Predicted molecular weight: 88 kDa.Can be blocked with STAT3 (phospho Y705) peptide (ab179551). Stimulation may be required to allow detection of the phosphorylated … community\u0027s wfWebApr 12, 2024 · Abstract：Objective: To clarify the interactions between phosphorylated Y705 and phosphorylated S727 in signal transducer and activator of transcription 3(STAT3). … community\u0027s wmWebOct 1, 2009 · While the levels of STAT3 protein remained constant, serving as a control for general protein expression, phosphorylation of STAT3, as well as levels of IL6 receptor … easy wire wrapped earrings tutorialWebThe transcriptional regulator STAT3 has key roles in vertebrate development and mature tissue function including control of inflammation and immunity. Mutations in human … easy wire wrap pendantWebThrough its regulation of gene activity, the STAT3 protein is involved in many cellular functions. It helps control cell growth and division (proliferation), cell movement … community\u0027s wh