Human perforin
Web22 mei 2015 · The activity of perforin is highly dependent on pH and Ca 2+; perforin is active at the neutral pH of the immunological synapse, but it is inactive under acidic … WebProduct Specific Information. Description: The dG9 antibody clone reacts with human perforin (pore-forming protein, pfp). Perforin is one of the cytolytic mediators present in the cytoplasmic granules of cytotoxic T lymphocytes (CTL) and natural killer cells (NK). Perforin is involved in the killing function by CTLs and NKs and has an important ...
Human perforin
Did you know?
Web22 okt. 2008 · Anti-human perforin antibodies were purchased from Diaclone (clone B-D48, Besancon, France) and BD Biosciences (clone δG9). It should be noted that for the remainder of this article we will address the perforin clone purchased from Diaclone as “D48” so as not to cause confusion with the δG9 clone purchased from BD Biosciences. WebWestern blot - Recombinant Human Perforin protein (ab114201) ab114201 on 12.5% SDS-PAGE stained with Coomassie Blue. Protocols. To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on. ...
WebDescription Perforin is a 70 kD cytolytic protein that is expressed in the cytoplasmic granules of cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells. Perforin is one of the major effector molecules used by cytotoxic T cells and NK cells to mediate targeted cell lysis. Product Details Technical data sheet Product Details Isotype Control WebPerforin is a 70 kD cytolytic protein that is expressed in the cytoplasmic granules of cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells. Perforin is one of the major …
Web22 jun. 2024 · Abcam’s Perforin (PRF1) Human in vitro ELISA (Enzyme-Linked Immunosorbent Assay) kit is designed for the quantitative measurement of Perforin in supernatant and buffered solutions. Note for serum & plasma quantification: high and non-linear detection level is found in Human serum and plasma samples. The high signal WebPerforin is one of the cytolytic factors present in the cytoplasmic granules of mouse cytotoxic T lymphocytes and natural killer cells1-3• We have determined the sequence of theN-terminal amino...
WebPerforin is a 70 kD cytolytic protein that is expressed in the cytoplasmic granules of cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells. Perforin is one of the major …
Web13 apr. 2024 · In conclusion, these results indicate the perforin/granzyme pathway as the major pathway to mediate cytotoxicity in CD19-CAR-NK92 cells. Chimeric ... NK-cells … topos solutionsWebPerforin is a pore forming protein with a mechanism of transmembrane channel formation similar to C9, and homology between perforin and C9 have been demonstrated. Studies … topos running shoes women\u0027sWeb4 dec. 1996 · Human perforin: rapid enrichment by immobilized metal affinity chromatography (IMAC) for whole cell cytotoxicity assays. Perforin, a potent pore … topos sncWebARG80173 Human Perforin ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human Perforin in Serum, Plasma, Cell culture supernatants. Tested Reactivity. Hu. Tested Application. ELISA. Specificity. No significant cross-reactivity or interference with Human IL-1 beta, IL-2, IL-3, IFN- gamma, TNF alpha, Fas, Fas-L, TRAIL. Target Name. topos sur le webWebDescription Perforin is a 70 kD cytolytic protein that is expressed in the cytoplasmic granules of cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells. Perforin is one of the major effector molecules used by cytotoxic T cells and NK cells to mediate targeted cell lysis. Product Details Technical Data Sheet (pdf) Product Details topos schaden agWebPerforin consists of three domains: 1 the MACPF domain, which includes the central machinery of pore formation, 2 the EGF-like domain, which forms a 'shelf-like' assembly … topos theory nlabWebDescription Perforin is a 70 kD cytolytic protein that is expressed in the cytoplasmic granules of cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells. Perforin is one of the major effector molecules used by cytotoxic T cells and NK cells to mediate targeted cell lysis. Product Details Technical data sheet Product Details Isotype Control topos theory johnstone