WebJun 29, 2011 · Cisplatin is the most common agent used in combination with RT, and is one of the best studied. The standard regimen is three-weekly high-dose (100 mg/m 2) cisplatin (three cycles) concurrent with RT ( 2, 3 ). However, cisplatin at a dose of 100 mg/m 2 with concomitant RT is associated with significant acute and late toxicities ( 2, 4, … WebIn addition, no significant difference in overall survival was seen in the matched cohorts. ChemoRT with either cisplatin or carboplatin was superior to RT alone and RT with concurrent cetuximab. In the multivariable model, the adjusted hazard ratio of CSM for carboplatin relative to cisplatin was 1.01 (95% CI, 0.79–1.28; P=.94).
Concurrent cisplatin-based chemoradiotherapy versus exclusive ...
WebNov 1, 2007 · All patients received pelvic external beam radiotherapy (EBRT) concurrently with weekly intravenous Cis-platinum chemotherapy (40 mg/m (2)) followed by brachytherapy (BT). The median dose of EBRT was 4500 cGy … WebFeb 16, 2016 · Cisplatin is standardly dosed in a three-weekly schedule of 100 mg/m 2 (total dose 300 mg/m 2) combined with standard RT [3,6,7,9,10]. However, a high-dose cisplatin regimen is associated with major toxic side effects (myelosuppression, neurotoxicity, ototoxicity, and nephrotoxicity). bridgeprep academy south campus
Concomitant Weekly Cisplatin and Radiotherapy for Head and …
WebIntroduction: The aim of this multicenter phase II trial was to evaluate the combination of oral vinorelbine and cisplatin with radiotherapy (RT) after cisplatin-docetaxel induction chemotherapy (CT) in patients with locally advanced non-small cell lung cancer (NSCLC). Patients and methods: Patients with previously untreated, inoperable, histologically or … WebJan 25, 2016 · Arm A represents concurrent pemetrexed-cisplatin (Pem-Cis) and thoracic radiation therapy (TRT) followed by consolidation pemetrexed. Arm B represents concurrent etoposide-cisplatin (Eto-Cis) and TRT followed by one of three consolidation chemotherapy regimens of choice: Eto-Cis, vinorelbine-cisplatin (Vin-Cis), or paclitaxel-carboplatin … WebTherapeutic efficacy of cisplatin-based treatment of late stage urothelial carcinoma (UC) is limited by chemoresistance. To elucidate underlying mechanisms and to develop new approaches for overcoming resistance, we generated long-term cisplatin treated (LTT) UC cell lines, characterised their cisplatin response, and determined the expression of … can\\u0027t turn airplane mode off windows 10